Chronic folate deficiency induces glucose and lipid metabolism disorders and subsequent cognitive dysfunction in mice
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چکیده
منابع مشابه
Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.
Folate deficiency and resultant increased homocysteine levels have been linked experimentally and epidemiologically with neurodegenerative conditions like stroke and dementia. Moreover, folate deficiency has been implicated in the pathogenesis of psychiatric disorders, most notably depression. We hypothesized that the pathogenic mechanisms include uracil misincorporation and, therefore, analyze...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0202910